Bismuth nitrate pentahydrate-induced novel nitration of eugenol
نویسندگان
چکیده
BACKGROUND Eugenol, the main constituent of clove oil possesses a number of medicinal activities. To enhance the medicinal property, structural modification is required. On the other hand, bismuth nitrate pentahydrate has been established as an excellent eco-friendly nitrating agent for several classes of organic compounds. RESULTS Bismuth nitrate pentahydrate-induced nitration of eugenol has been investigated very thoroughly. Twenty five different conditions have been studied. The microwave-induced solvent-free reaction has been identified as the best condition. CONCLUSIONS Spectral analyses confirm that 5-nitroeugenol is the sole product in all the cases. No oxidized or isomerized product could be detected.
منابع مشابه
Bismuth nitrate-induced microwave-assisted expeditious synthesis of vanillin from curcumin
BACKGROUND Curcumin and vanillin are the two useful compounds in food and medicine. Bismuth nitrate pentahydrate is an economical and ecofriendly reagent. METHOD Bismuth nitrate pentahydrate impregnated montmorillonite KSF clay and curcumin were subjected to microwave irradiation. RESULTS Microwave-induced bismuth nitrate-promoted synthesis of vanillin from curcumin has been accomplished in...
متن کاملNitration Ortho Dihydroxyl Benzene (Catechol) Using Bismuth Nitrate on the Solid Phase Montmorillonite
Nitro catechols via 2 hydroxyl group and a nitro group have a wide range of functions including reagents form stable complexes with more than 40 elements in the fields of analytical chemistry, biochemistry, coordination chemistry, environmental chemistry, atrium exploration, organic chemistry, pharmacy, etc. Moreover, the nitro to amine recovery has a potential function in different fields. In ...
متن کاملipso-Nitration of arylboronic acids with bismuth nitrate and perdisulfate.
An efficient and one pot synthetic method of ipso-nitration of arylboronic acids has been developed. The high efficiency, general applicability, and broader substrate scope including heterocycles and functional groups make this method advantageous. Due to its simplicity, we expect to find application of this method in synthesis.
متن کاملA microwave-assisted bismuth nitrate-catalyzed unique route toward 1,4-dihydropyridines.
The classical Hantzsch reaction is one of the simplest and most economical methods for the synthesis of biologically important and pharmacologically useful 1,4-dihydropyridine derivatives. Bismuth nitrate pentahydrate under microwave irradiation is proven to act as a very efficient catalyst for a one-pot, three-component synthesis of 1,4-dihydropyridines in excellent yields from diverse amines/...
متن کاملNanosheets of BiOCl Incorporated in Microflowers: Microwave Assisted Synthesis and Dye-Photosensitized Removal of Pollutants
BiOCl microflowers were synthesized using bismuth nitrate pentahydrate and sodium chloride by microwave (MW) assisted synthesis method for 23 minutes at 180 W. Scanning electron microscopy (SEM) studies revealed a unique morphology of flower-like assemblies comprised of nanosheets. The X-ray diffraction (XRD) pattern showed that a highly pure and crystalline phase has been obtained. The energy ...
متن کامل